A safe and effective topical spray suitable for general antiseptic purposes on the skin of most animals. It can be used to control topical infection of the skin, keeping wounds dry and covered with a protective residue film of iodine to provide prolonged activity. BUFFERED IODINE SPRAY may be used in numerous surgical procedures and as a topical agent for various dermal and mucosal infections such as wounds, cuts, abrasions, burns, ringworm, navel disinfection in newly born animals, castration and docking wounds, udder wounds and cut teats.